منابع مشابه
Malaria sporozoites and circumsporozoite proteins bind specifically to sulfated glycoconjugates
Circumsporozoite (CS) proteins, which densely coat malaria (Plasmodia) sporozoites, contain an amino acid sequence that is homologous to segments in other proteins which bind specifically to sulfated glycoconjugates. The presence of this homology suggests that sporozoites and CS proteins may also bind sulfated glycoconjugates. To test this hypothesis, recombinant P. yoelii CS protein was examin...
متن کاملDetection and characterization of excretory/secretory proteins from Toxoplasma gondii by monoclonal antibodies.
Excretory/secretory proteins (ESP) from Toxoplasma gondii were analyzed to define the function in the penetration process into host cells. Whole ESP obtained at 37 degrees C were composed of 15 bands with molecular mass of 110, 97, 86, 80, 70, 60, 54, 42, 40, 36, 30, 28, 26, 22, and 19 kDa. Five ESP of 86, 80, 42, 36, and 28 kDa were reacted with monoclonal antibodies (mAb), named as Tg386 (mic...
متن کاملSecretory traffic in the eukaryotic parasite Toxoplasma gondii
Name a single-celled eukaryote that boasts a small genome size, is easily cultivated in haploid form, for which a wide variety of molecular genetic tools are available, and that exhibits a simple, polarized secretory apparatus with a well-defined endoplasmic reticulum and Golgi that can serve as a model for understanding secretion. Got it? Now name a cell with all these attributes that contains...
متن کاملProteins That Bind Sulfated Glycosaminoglycans - Essentials of Glycobiology - NCBI Bookshelf
Glycosaminoglycans bind to many different classes of proteins mostly through electrostatic interactions between negatively charged sulfate groups and uronic acids and positively charged amino acids in the protein. This chapter focuses on examples of glycosaminoglycan (GAG)-binding proteins, methods for measuring GAG–protein interaction, and information about three-dimensional structures of the ...
متن کاملHuman Toxoplasma gondii-specific secretory immunoglobulin A reduces T. gondii infection of enterocytes in vitro.
Whey from 17 women (four acutely infected with Toxoplasma gondii, eight chronically infected, and five uninfected) was studied. T. gondii-specific secretory IgA antibodies were demonstrated by ELISA in whey from acutely infected and one of eight chronically infected women. Such antibodies to tachyzoite proteins of < or = 14, 22, 26-28, 30, 46, 60, 70-80, and > 100 kD (eliminated by protease but...
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ژورنال
عنوان ژورنال: Glycobiology
سال: 2012
ISSN: 0959-6658,1460-2423
DOI: 10.1093/glycob/cws134